The main thing about P2P meth is that there's so much of it (2022)

Since around 2009, methamphetamine production in the US shifted from ephedrine-based synthesis to phenylacetone (P2P)-based synthesis, following restrictions on pseudoephedrine sales and Mexican bans on precursor chemicals. Some observers, including journalist Sam Quinones, have suggested that P2P methamphetamine may have different chemical properties that could cause more severe psychological effects like paranoia and social withdrawal compared to older ephedrine-based meth, which was described as more of a party drug that allowed users to maintain jobs and housing.